Brain Cell Death May Cause Multiple Sclerosis And Cause Autoimmune Response Against Myelin
Multiple sclerosis (MS) may be triggered by the death of myelin-producing brain cells (oligodendrocytes), leading to an autoimmune response against myelin. The findings come from researchers at the University of Chicago and Northwestern Medicine who developed novel mouse models to conduct their studies. The researchers found that the death of oligodendrocytes triggers an autoimmune response against myelin, triggering multiple sclerosis-like symptoms in mice. On the other hand, the researchers found that the reaction can be prevented by using specially developed nanoparticles even after brain cells are lost. These nanoparticles are now being developed in clinical trials with the potential for future treatments for humans. Co-senior author Brian Popko said, “Although this was a study in mice, we first demonstrated one mechanism that could induce MS - the death of the cells responsible for generating myelin. cause autoimmune activation response against. Protecting t...